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Crohn’s Disease

Crohn’s disease is a form of inflammatory bowel disease (IBD). It usually affects the intestines, but may occur anywhere from the mouth to the end of the rectum

See endoscopic photos of Crohn’s Disease

The top image shows a barium X-ray of the transverse colon of a patient suffering from Crohn’s disease. Crohn’s disease causes inflammation, thickening and ulceration (red mottled region at upper left) of the intestinal tract, most often the small intestine and the colon (large intestine). Its cause is unknown. Symptoms include abdominal pain, diarrhea and the malabsorption of food, leading to weight loss. Crohn’s disease is treated with antibiotics and anti-inflammatory drugs. Surgical removal of inflamed regions of the intestine is sometimes also required. Barium is a radio-opaque medium that allows soft structures to be seen on X-ray.

See barium x-rays of Crohn’s Disease

Below this are 4 images taken with a pill camera that show the lining of the ileum which is the last part of the small intestine. It is red and inflamed due to Crohn’s disease. The inflammation has led to narrowing (stricture) of the intestinal passage. 

Treatment normally involves controlling the symptoms and maintaining remission where possible, using anti-inflammatory drugs and immunosupressants. Surgical removal of inflamed regions of the intestine is sometimes also required.

Images above © Science Source

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